Abstract
TMSOMs (5 equiv.)-BF 3·Et 2O (1 equiv.) complex was studied for the selective cleavage of bicyclic ketal and a useful method was found for the preparation of 2,3,6-trisubstituted pyridine in good yield. The bicyclic ketal was cleaved and rearranged to 1,5-diketone which was then reacted with nitrile affording pyridine as a sole product in one-flask.
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