Abstract
Asymmetric heterogeneous hydrogenation of acetylacetone was applied for the preparation of both enantiomers (2 R,4 R and 2 S,4 S) of 2,4-bis(diphenylphosphino)pentane (BDPP). Among the chiral phosphines prepared up to now BDPP appears to be unique in the sense that its rhodium(I) complexes serve as effective homogeneous asymmetric hydrogenation catalysts not only for the reduction of Z-α-amidoacrylic acids but also for the reduction of α-ethylstyrene, acetophenone, and acetophenonebenzylimine. The analogous phosphinite ligand BDPOP yields a less selective catalyst.
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