A facile green synthesis of Ag@MnO2 nanoparticles using Martynia annua plant extract and their biological activity and catalytic reduction of dye

Abstract

The Ag@MnO2 NPs were characterized by UV, FTIR, HRTEM, SAED, and EDX analysis. UV analysis revealed the characteristic wavelength absorption maxima at 425 nm, which confirmed the synthesis of Ag@MnO2 NPs. Martynia annua plant extract presented phytochemical compounds that act as reducing and capping agents in the synthesis of Ag@MnO2 NPs, as confirmed by FT-IR analysis. HRTEM analysis to determine the Ag@MnO2 NPs morphology images showed the spherical shape of NPs with sizes from 1 to 8 nm. The crystalline nature of Ag@MnO2 NPs was identified using SAED and EDX analysis revealed the composition of these synthesized NPs. In-vitro antioxidant activities of Ag@MnO2 NPs were evaluated using a DPPH assay for the significant radical scavenging ability of these NPs. Our findings revealed that M.annua plant-mediated Ag@MnO2 NPs have been highly active against both bacterial and fungal strains. The BSA and EA methods for inhibition of albumin denaturation were investigated for their anti-inflammatory activity. The Ag@MnO2 NPs showed superior activity as anti-inflammatory agents, reduced the viability of the human lung cancer cell line A549 up to 9.92 % at a concentration of 500 µg/ml, and exhibited a good cytotoxic effect. In the presence of NaBH4, the Ag@MnO2 NPs showed excellent catalytic degradation activity against Fuchsin basic dye.