Abstract

A highly selective cleavage of prenyl esters has been achieved in high yields using CeCl3·7 H2O-NaI in refluxing acetonitrile under neutral conditions. This method is mild and compatible with a wide variety of functional groups such as BOC, Cbz, acetate, allyl, benzyl, tetrahydropyranyl, PMB ethers, allyl, methyl, and benzyl esters present in the molecule.

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