Abstract
A facile and general synthesis of a series of new troplonyl-substituted chalcone derivatives by Claisen–Schmidt condensation reaction from 3-acetyltropolone and substituted benzaldehydes as well as pyridine aldehydes is described. The method using 5% aq. KOH as catalyst and 50% aq. methanol as solvent is attractive since it specifically generates (E)-isomers with high yields under mild reaction conditions.
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