Abstract
Abstract magnified imageA series of novel pyrimido[5,4‐b][4,7]phenanthroline‐9,11(7H,8H,10H,12H)‐dione derivatives were synthesized via microwave‐assisted three‐component reactions of barbituric acid, aldehyde, and quinolin‐6‐amine in DMF without catalyst. This facile synthesis not only offers an economical and efficient synthetic strategy to this class of significant compounds but also enriches the investigations on microwave‐assisted multicomponent reactions. Moreover, this protocol has the prominent advantages of short reaction time, good yields, low cost, easy operation, as well as environmental‐friendliness. J. Heterocyclic Chem., 46, 563 (2009).
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