Abstract
Herein, a fast, simple, efficient, and eco-friendly procedure for the synthesis of 4-aryl-3-(trifluoromethyl)-1H-1,2,4-triazole-5(4H)-thiones under microwave irradiation is introduced. The current strategy enabled the synthesis of triazole-5(4H)-thiones scaffolds at 70 °C under shorter reaction times through the sequential nucleophilic addition and then intramolecular ring closing reactions between trifluoromethyl arylacetimidohydrazides and carbon disulfide in high yields.
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