Abstract

A near-infrared fluorescent probe (NUST-Cy-1) was disclosed here, which displays ratiometric and dual-channel response for Cu2+ (λex1 = 450 nm, λex2 = 750 nm) with large Stokes shifts (143 nm, 375 nm, 75 nm respectively). This probe demonstrates high sensitivity with low detection limit (1.4 μM) and selectivity for Cu2+ detection. Furthermore, fluorescent imaging of Cu2+ in vitro and vivo were successfully achieved.

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