Abstract

Direct ink writing is a versatile bioprinting technology to fabricate soft models, where soft materials are extruded through an orifice and settled on a platform to form multi-layered structures. An extruded filament is the basic unit of the extrusion process which can affect the overall quality of model fabrication. Here, we report a novel method to evaluate the quality of printing via introducing two dimensionless indices, which independently reflect the average width and the width variation of extruded filaments. Different concentrations of Pluronic® F127 materials were used to print zigzag multi-layer models to understand the influences of printing parameters on both indices. Results show the dual-index method can semi-quantitatively expose the morphological differences of extrudates under altered printing conditions, providing a potential evaluation tool for the quality assessment of direct ink writing.

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