Abstract
Nanoparticles (NPs) with integrated functionalities of targeting, therapy, imaging contrast and biocompatibility have shown promise for application in improved disease diagnosis and therapy. Herein, we report a theranostic agent based on a narrow-bandgap small molecule, benzo[1,2-c;4,5-c']bis[1,2,5]thiadiazole-4,7-bis(9,9-dioctyl-9H-fluoren-2-yl)thiophene (denoted as BBT-2FT), with the strong absorption of near-infrared (NIR) light. Colloidal nanoparticles composed of BBT-2FT showed a photoacoustic signal intensity ten times higher than that of blood, and high photothermal conversion efficiency (η = 40%) under the irradiation of 808 nm laser light, which killed over 90% of HeLa cells in 10 min.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
