Abstract
Drosophila is an emerging model organism for studying the effects of genetics, diet, and suspected environmental obesogens on the regulation of metabolism and physiological function. Obesogens are chemicals that are suspected endocrine disruptors thought to interfere with mechanisms involved in lipid metabolism and may be partly responsible for the increase in obesity. This teaching laboratory uses a modified version of the floating larvae or density assay originally developed as a genetic screen in Drosophila that identified genes that influence the metabolism and accumulation of lipids. This is a simple, inexpensive assay that can be used by undergraduate students to screen potential environmental obesogens by adding them to a standard fly diet and recording results that a highly reproducible and easily observed. The assay is suitable for incorporation into a course based undergraduate research project (CURE).This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.
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