Abstract
In this issue of Cell Chemical Biology, Lion etal. (2017) report a multiplexed labeling method to visualize plant cell wall lignification invivo. This approach uses two different lignin precursor analogs tagged with azide and alkyne reporters that can be independently incorporated into cell walls, then differentially derivatized invivo via two bioorthogonal click reactions: strain-promoted and copper-assisted azide-alkyne cycloadditions.
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