Abstract
The ABS consensus guidelines for high-dose-rate (HDR) prostate brachytherapy (Yamada Y et al, Brachytherapy 11 (2012)) suggest 11 different dose constraints for the urethra. Data from RTOG 0321 (Hsu I et al, PRO 4 (2014)) suggests that various doses along the urethra dose volume histogram (DVH) correlate with genitourinary (GU) adverse events. The Purpose of this study is to evaluate whether a single urethral constraint of D0.1cc < 110% could meet all the other proposed ABS urethral constraints and to evaluate the heterogeneity/similarities of other portions of the DVH when only optimizing to a single constraint.
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