Abstract

Discarded hearts from brain-dead donors and donors after circulatory death may represent unutilized sources of organs for transplantation; however, demonstration of adequate myocardial function prior to transplantation is necessary. Ex vivo heart perfusion (EVHP) provides an opportunity for such functional assessment. The optimal method of oxygen delivery to meet the metabolic demands of a heart in working mode during EVHP has not been established. We sought to determine the impact of different oxygen carriers on the preservation of myocardial function during EVHP.

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