Abstract
Background and Aims: Since more effective, but expensive, lipid lowering medication (like PCSK9 inhibitors) is available for familial hypercholesterolemia (FH) patients, biomarkers are urgently needed to identify patients with high residual risk for developing CVD. While studying atherosclerosis development in a FH porcine model, we discovered a specific LDL profile that predicted the severity of atherosclerosis development.
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