Abstract
The major transmission route of hepatitisB virus (HBV) is perinatal, especiallyduring delivery in endemic areas. To decrease the prevalence of and complicationsassociated with chronic hepatitisB, universal vaccination and maternalscreening for hepatitis B serumantigen (HBsAg) are essential. Almost5% of newborn infants are inadequatelyprotected by current immunoprophylacticmeasures, and this figure mayrise to 50% if prophylaxis is poor or thematernal HBV DNA load is high (> 107IU/mL) [1].
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