A Dinuclear Dysprosium Complex as an Air-Stable and Recyclable Catalyst: Applications in the Deacetylation of Carbohydrate, Aliphatic, and Aromatic Molecules.

Abstract

Two dinuclear DyIII complexes, [Dy2 (hmb)2 (OTf)2 (H2 O)4 ]⋅HOTf⋅2 THF (A⋅HOTf⋅2 THF) and [Dy2 (hmi)3 (H2 O)2 ]⋅2 HOTf (B⋅2 HOTf), have been synthesized by the reaction of Dy(OTf)3 and the Schiff-base ligands H2 hmb (N'-(2-hydroxy-3-methoxybenzylidene)benzohydrazide) or H2 hmi ((2-hydroxy-3-methoxyphenyl)methylene isonicotinohydrazine). Disarmed glycosyl trichloroacetimidates can be activated by complex A in the synthesis of 1,2-trans-glycosides with primary and secondary acceptors. This method offers an efficient route to selectively deacetylated monosaccharides and disaccharides in high yields and a green catalyst that can be easily recycled and reused.