A Detailed Study of Covid-19 (Emphasizing its Genomic Variants, Pathogenicity, Phylogenetic Analysis, Epidemiology, and Clinical Measures)

Abstract

Covid-19 (Coronavirus) had spread all over the world. Around 213 countries were affected by the deadly virus and encountered a mob of dead. After analyzing the genome, we can say that the Coronavirus originates in bats and gets transmitted to humans. Although the intermediate source of origin and transmission to humans is unknown, rapid human-to-human transmission has been evinced. SARS-CoV-2 is phylogenetically related to a group of bat viruses known to cause severe acute respiratory syndrome (SARS-CoV). Both viruses (SARS-CoV and SARS-CoV2) belong to the same family of beta coronaviruses. The first case of SARS-CoV2 infection was reported from Wuhan, China. Till now, there have been 577,018,226 confirmed cases of Covid-19 worldwide. More than 6 million people have succumbed to this deadly disease worldwide. Presently, the urgent need to develop a drug and vaccine that could cure this disease is fulfilled. This current review summarizes the origin of SARS-CoV2, its genome structure, pathogenicity and phylogenetic analysis of the virus, and its epidemiology. We have also discussed the existing drugs and approved vaccines that are presently treating humanity. This review aims to compact every possible information regarding Covid-19.