Abstract
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Highlights
The Dermal Biomarker Patch (DBP) platform e ciently captures transcriptomes of >7,000 biomarkers from the lesional skin of psoriasis patients in su cient quantities for next-generation sequencing protocols
Using the DBP, a total of 416 transcriptomes were collected from 24 di erent body areas; each transcriptome was comprised of ~7,000 biomarkers
Measurements were made of the gene detection rate and mRNA yield
Summary
PhD, Stephen Boyd, BS, Eric Andrade, BS, Christian Abaya, BS, Yipeng Wang, MD, PhD, and Byung-In Lee, PhD Mindera Health, 5795 Kearny Villa Road, San Diego, CA 92123 The Dermal Biomarker Patch (DBP) platform e ciently captures transcriptomes of >7,000 biomarkers from the lesional skin of psoriasis patients in su cient quantities for next-generation sequencing protocols. There was no significant body-site variation observed, in contrast to stratum corneum tape stripping.* This platform makes precision medicine in dermatology a reality. It provides a powerful tool for doctors, researchers, and patients to better understand the skin.
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