Abstract

Arterial stenosis will reduce the blood flow to various organs or tissues, causing cardiovascular diseases. Although there are mature diagnostic techniques in clinical practice, they are not suitable for early cardiovascular disease prediction and monitoring due to their high cost and complex operation. In this paper, we studied the electromagnetic effect of arterial blood flow and proposed a method based on the deep neural network for arterial blood flow profile reconstruction. The potential difference and weight matrix are used as inputs to the method, and its output is an estimate of the internal blood flow velocity distribution for arterial blood flow profile reconstruction. Firstly, the weight matrix is input into the convolutional auto-encode (CAE) network to extract its features. Then, the weight matrix features and potential difference are combined to obtain the features of the blood velocity distribution. Finally, the velocity features are reconstructed into blood flow velocity distribution by a convolution neural network (CNN). All data sets are obtained from a model of the carotid artery with different rates of stenosis in a uniform magnetic field by COMSOL. The results show that the average root mean square error of the reconstruction results obtained by the proposed method is 0.0333, and the average correlation coefficient is 0.9721, which is better than the corresponding indicators of the Tikhonov, back propagation (BP) and CNN methods. The simulation results show that the proposed method can achieve high accuracy in blood flow profile reconstruction and is of great significance for the early diagnosis of arterial stenosis and other vessel diseases.

Highlights

  • Introduction iationsAccording to investigation [1], cardiovascular diseases such as coronary artery stenosis, coronary heart disease and atherosclerosis have become major diseases that seriously endanger human health

  • We proposed an arterial blood flow profile reconstruction method based on deep neural networks (DNNs), with convolutional auto-encode (CAE) and convolution neural network (CNN)

  • They are feature extraction of the weight matrix based on the convolutional auto-encoder (CAE) network, data domain transformation and blood flow velocity reconstruction based on the convolutional neural network (CNN)

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Summary

Introduction

Introduction iationsAccording to investigation [1], cardiovascular diseases such as coronary artery stenosis, coronary heart disease and atherosclerosis have become major diseases that seriously endanger human health. It is of great value to develop a safe and non-invasive method to monitor blood flow velocity status for the early prevention of common cardiovascular diseases. Common diagnostic methods for arterial stenosis include digital subtraction angiography (DSA) [2], nuclear magnetic resonance angiography (MRA) [3], spiral CT angiography (CTA) [4] and ultrasonic examination [5]. These methods can detect the degree and range of arterial stenosis, but their results depend on the experience of operators, Licensee MDPI, Basel, Switzerland

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