Abstract

Deep brain stimulation (DBS) therapy has been widely used in clinical practice for the treatment of neurological diseases and has achieved significant therapeutic effect. In this paper, aiming at the social problem of drug addiction, we design an electrical stimulation system which can be used in animal experiments, carry out the memory extinction experiment of addiction in rats, and explore the effective electrical stimulation parameters. The DBS system consists of a rechargeable battery and a PCB stimulation circuit composed of discrete devices. In animal experiments, the power consumption of the circuit is 0.36mW in the electrical stimulation stage. Theoretically, the circuit can work continuously for more than 100 days with a 3.7V 250mAh lithium battery. The stimulation circuit is highly programmable and the output stimulation current ranges from 100μA to 5000μA with a 20μA current resolution.

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