Abstract
In this study, a novel missense (NM_174579:c.1201C>T) mutation in exon 6 at the bovine <I>POU1F1</I> locus is reported, which results in p.S284F, namely, Ser (TCT) > Phe (TTT) at position 284 of the mature protein. A <I>Dde</I>I PCR-RFLP was used to determine the genotypes. The polymorphism was studied in eight Chinese cattle breeds (Nanyang, <I>n</I> = 251; Qinchuan, 149; Jiaxian Red, 144; Chinese Holstein, 61; Luxi, 57; Angus, 49; Jinnan, 60; Guyuan, 192). The frequencies of the <I>POU1F1 T</I> allele in the analyzed populations ranged from 0.010 to 0.053. The relationships between the <I>Dde</I>I polymorphism and growth traits and body sizes were analyzed by adjusted linear model in 251 Nanyang cattle. Fixed effects of marker genotype, birth year, season of birth (spring vs. fall), age of dam, sire, farm and sex, and random effects of an animal were included. Statistical evaluation revealed no significant relationships between this polymorphism and birth weight, body weight and average daily gain for different growth periods (6-month old, 12-month old, 18-month old and 24-month old) body height, body length, heart girth and height at the hip cross for different growth periods (<I>P</I> > 0.05).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
