Abstract

Background: Fine Needle Aspiration Cytology (FNAC) is important for pre-operative diagnosis of benign and malignant thyroid lesions. It is usually the first line of investigation and a minimally invasive diagnostic procedure whose essential role is to diagnose and distinguish benign from malignant lesions. Thus the present study was undertaken to determine sensitivity, specificity and accuracy of FNAC in the diagnosis of thyroid lesions and to correlate cytological findings with histopathology. Methods: A prospective study was conducted in a tertiary care centre to study FNAC of thyroid lesions along with its histopathological correlation over a period of 2 years starting from June 2013 to June 2015 Result: 56(93%) patients were females and 4(7%) patients were males. Patients age ranged from 15 to 65 years .Commonest lesion encountered in thyroid gland was colloid goitre, while papillary carcinoma was the most frequent malignant lesion. Cyto-histopathological correlation of 60 cases was done. Sensitivity ,specificity and diagnostic accuracy of the study for malignant lesions was 96.36%,100%,and 96.66% respectively. Conclusion: FNAC is a safe, simple, highly accurate, economical method for evaluation of palpable thyroid lesions. There is almost perfect cyto-histopathological concordance and the results are consistent with those available in the literature. FNAC helps in avoiding unnecessary surgeries in patients diagnosed to have a benign pathology based on cytology. Thus FNAC serves as a useful screening test to triage thyroid lesions before surgery. DOI: 10.21276/APALM.1154

Highlights

  • Head and neck lesions are very common and they range from inflammatory lesions to malignancies

  • Majority of the Cytohistopathological Correlation of Thyroid Lesions patients are in the age group of 21-40 years followed by 41-60years

  • The present study showed 96.36% sensitivity, 100% specificity and 96.66% diagnostic accuracy in detecting malignant tumors

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Summary

Introduction

Head and neck lesions are very common and they range from inflammatory lesions to malignancies. Among head and neck lesions thyroid lesions are most common with a prevalence rate ranging from 4-7%.[1]The majority of clinically diagnosed thyroid lesions are non-neoplastic ;only 5-30%,are malignant and require surgical intervention. [4] the main aim of this diagnostic procedure in thyroid lesions is to detect the thyroid neoplasms for surgical resection and to identify non neoplastic lesions that may be managed conservatively. Fine Needle Aspiration Cytology (FNAC) is important for pre-operative diagnosis of benign and malignant thyroid lesions. It is usually the first line of investigation and a minimally invasive diagnostic procedure whose essential role is to diagnose and distinguish benign from malignant lesions. The present study was undertaken to determine sensitivity, specificity and accuracy of FNAC in the diagnosis of thyroid lesions and to correlate cytological findings with histopathology

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