Abstract
A novel curcumin activated carboxymethylcellulose–montmorillonite nanocomposite is reported. A superabsorbent biopolymer; carboxymethyl cellulose (CMC) was used as an emulsifier for curcuminwhich is a turmeric derived water insoluble polyphenolic compound with antibacterial/anti-cancer properties. Montmorillonite (MMT) nanoclay was incorporated in the formulation as a matrix material which also plays a role in release kinetics. It was observed that water solubility of curcumin in the nanocomposite has significantly increased (60% release within 2h and 30min in distilled water at pH 5.4) compared to pure curcumin. The prepared curcumin activated carboxymethylcellulose–montmorillonite nanocomposite is suitable as a curcumin carrier having enhanced release and structural properties.
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