Abstract

BackgroundPsychosocial models including illness perception might explain individual differences in health-related quality of life (HRQoL) and daily functioning in chronically ill patients. The aim of this study was to assess the association of illness perception among rheumatoid arthritis (RA) patients with physical and mental HRQoL, adjusted for demographic variables, clinical variables and social support.MethodsA cross-sectional study conducted at a Viennese rheumatology outpatient clinic on 120 RA patients. Participants completed questionnaires on demographic and clinical characteristics, HRQoL (SF-36 Questionnaire), illness beliefs (Brief Illness Perception Questionnaire) and social support (Social Support Scale-8). Analyses were performed with multivariate linear regression.ResultsThe mean physical was lower (38.38) than the mean mental SF-36 summary score (46.94). In univariate analysis, all domains of illness perception except belief in a chronic disease course were associated with physical and mental HRQoL. In multivariate analyses, illness perception accounted for 51% of variance in physical HRQoL. A stronger belief in the consequences of RA (consequences, β = − 0.33) and a stronger belief in repeated disease recurrence (timeline cyclical, β = − 0 .31) were significantly associated with physical HRQoL in the fully adjusted model. Illness perception accounted for 45% of variance in mental HRQoL. Emotional representation (β = − 0 .27) and fatigue (β = − 0 .36) were significantly associated with mental HRQoL in the fully adjusted model.ConclusionThis study highlights the importance of RA patients’ beliefs about their illness and symptoms in relation to HRQoL. Identification of patients’ perception of RA may be a way to positively influence disease outcomes such as quality of life as illness perception is amenable to intervention.

Highlights

  • Rheumatoid arthritis (RA) is a chronic systemic disabling condition with a global prevalence of an estimated 0.2–1.0% [1] that can lead to impairment in activities of daily living and work productivity and compromise the overall well-being of rheumatoid arthritis (RA) patients [2]

  • The different types of RA medication were included as dichotomous variables and illness perception, health-related quality of life (HRQoL) and social support were included as continuous variables as listed in Tables 2 and 3

  • Mental health-related quality of life Univariate analysis (Table 3) revealed that the variables age and monthly net income, number of additional medications, presence of co-morbidity, pain, disease activity, functional disability, fatigue, positive as well as detrimental social interactions and all dimensions of illness perception except timeline were significantly associated with mental HRQoL at the p < 0.2 significance level and were included in the multivariate analysis (Table 5)

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Summary

Introduction

Rheumatoid arthritis (RA) is a chronic systemic disabling condition with a global prevalence of an estimated 0.2–1.0% [1] that can lead to impairment in activities of daily living and work productivity and compromise the overall well-being of RA patients [2]. Berner et al Health and Quality of Life Outcomes (2018) 16:238 view and rarely includes a patient’s overall health-related quality of life (HRQoL) [7, 8]. Despite similar levels of disease activity and severity, rheumatologists have observed individual variations in HRQoL. Psychosocial models including illness perception might explain individual differences in health-related quality of life (HRQoL) and daily functioning in chronically ill patients. The aim of this study was to assess the association of illness perception among rheumatoid arthritis (RA) patients with physical and mental HRQoL, adjusted for demographic variables, clinical variables and social support

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