A CROSS SECTIONAL STUDY TO EVALUATE ACUTE KIDNEY INJURY IN SCRUB TYPHUS PATIENTS

Abstract

Objective: This study was conducted with the objective of estimating the incidence and severity of acute kidney injury (AKI) in scrub typhus patients. Methods: This was a cross-sectional study conducted on 90 patients diagnosed with scrub typhus in a tertiary care center. Basic demographic and treatment details of the patients were recorded. Routine hematological investigations and biochemical profiles were performed upon admission and follow-up. AKI was defined and classified based on the RIFLE criteria. Results: The mean age of the patients was 49.0±19.5 year and a female preponderance was observed. The hemoglobin level was significantly lower in AKI patients as compared to non-AKI patients. Meanwhile, there was a significant increase in mean TLC count, C-reactive protein, and total bilirubin in AKI patients as compared to non-AKI patients. Was significantly higher as compared to those without AKI. Increasing age, Intensive care unit admission, shock, urinary abnormalities, and mechanical ventilation were the factors significantly associated with AKI. Conclusion: AKI is a frequently reported complication in scrub typhus patients. In evaluating febrile illnesses associated with AKI, scrub typhus should be considered.