Abstract
Aims: The study is aimed to determine the distribution pattern of the ABO grouping and Rh typing among blood donors in Great Eastern Medical School and Hospital, Srikakulam and to correlate it with the available data from studies inside India and other parts of the world. Materials and Method: The present study was conducted at Great Eastern Medical School and Hospital, Srikakulam, a tertiary care teaching hospital. All blood donors were done counseling as per NACO guidelines and considered fit for blood donation were included in this study. A total of 5868 blood donors was considered physically screened and declared fit and accepted for blood donation. Results: Out of 5868 donors, 5850 (99.6%) were males and 18 (0.4%) were females. The majority of donors belonged to the age group 26-35 years. The commonest ABO blood group present was B (36.4%) followed by O (35.08%), A (24.4%), and AB (4.12%) while 5743 (97.86%) donors were Rh-positive and 125(2.13%) donors were Rh-negative. Conclusion: Knowledge of the distribution pattern of the different blood groups is very crucial for blood banks and blood transfusion services which significantly contribute to the Health System of the Nation. Knowledge of blood group distribution is important for clinical studies, geographical information, and forensic studies in the general population.
Highlights
Aims and ObjectivesHuman red blood cells contain on their surface a series of carbohydrate structures of glycoproteins and glycolipids, which represent blood group antigens
The first human blood group system to be discovered by Landsteiner was the ABO blood group system in 1901. [3]
The commonest ABO blood group present was B (36.4%) followed by O (35.08%), A (24.4%) and AB (4.12%) [Table 1] while 5743 (97.86%) donors were Rh-positive and 125(2.13%) donors were Rhnegative. [ Table 2 ]
Summary
Human red blood cells contain on their surface a series of carbohydrate structures of glycoproteins and glycolipids, which represent blood group antigens. These antigens are genetically controlled and are inherited in early fetal life by Mendelian manner and remain the same until death [1]. International Society of Blood Transfusion has identified 30 blood group system genes. The most important blood group systems are ABO and Rh [2]. The first human blood group system to be discovered by Landsteiner was the ABO blood group system in 1901. To know the distribution frequency of different blood groups in healthy and adult blood donors, to compare this study data with other study data in other states of India and all over the world, and to make documentation of a blood group data registry
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