A CROSS SECTIONAL STUDY ON C-REACTIVE PROTEIN LEVELAMONG OVERWEIGHT AND OBESE CHILDREN ATTENDING A TERTIARY CARE HOSPITAL OF DISTRICT KANPUR

Abstract

Introduction- The global prevalence of overweight and obesity in children and adolescents has increased substantially over the past several decades. Accumulating evidence suggests that Hs-CRP, which is also found within macrophages of atheromatous plaques. However, there is no much data available that guarantee its utility as a marker of cardiovascular risk in obese children and adolescents. Hence, the present study was taken up to assess the metabolic abnormalities and its association with hsCRP in obese children and adolescents. Methodology-Present cross sectional study was conducted on 100participants attending the tertiary care hospital of District Kanpur and 5ml fasting sample had been collected after overnight fasting and data was entered in Microsoft excel and analysed in SPSS 15.0 using ANOVAand unpaired student t test.Result- among cases group there were 4 participants among the age group of 4-8yrs,10 in the age group of 9-13yrs,23 in the age group of >13yrs while in control group there were 3 participants ampong 4-8yrs of age and 28 in 9-13 yrs ,32 participants among the age of >13yrs. On applying independent sample T-test, we could not established correlation between age and Hs-CRP (p value >0.05).Conclusion- obese children and adolescents have signicantly increased hsCRP compared with a normal weight group. Early intervention and prevention of obesity in children and adolescents decreases cardiovascular disease in later life