Abstract

Introduction: The apical periodontitis possesses an association with the increased inflammatory markers levels, which contribute to the systematic immune response, leading towards systematic inflammation. The endodontic infections were reported to contribute to the CVD via the metastatic pathways however, there is a requirement to analyse the impact of endodontic infections on the pathogenesis of the cardiovascular disease. Aim:This research aims to assess the impact of endodontic infections on the pathogenesis of the cardiovascular disease. Material andMethod:This research was conducted using a cross-sectional research design by recruiting N=120 inpatients and outpatients visiting the healthcare organisation located in Saudi Arabia. Results:The endodontic infections are likely to increase the overall inflammatory burden, which might increase the risk of CVD among the individuals. Due to the multifactorial aetiology of CVD, the oral diseases are perceived to possess associated with the CVD. Thestatistical analysis revealed that there is no association between the presence of the lesion of endodontic origin and cardiovascular diseases. Conclusion:There is no association between the presence of the lesion of endodontic origin and cardiovascular diseases.

Highlights

  • The apical periodontitis possesses an association with the increased inflammatory markers’ levels, which contribute to the systematic immune response, leading towards systematic inflammation

  • CrossDisease, the metastatic pathways; there is a requirement to analyse the impact of endodontic infections on the pathogenesis of the cardiovascular disease

  • Conclusion:There is no association between the presence of the lesion of endodontic origin and cardiovascular diseases

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Summary

RESEARCH ARTICLE

A CROSS-SECTIONAL STUDY OF THE IMPACT OF ENDODONTIC INFECTIONS ON THE PATHOGENESIS OF CARDIOVASCULAR DISEASE. 1. Consultant in restorative and implant Dentistry, Program director for Dental Implant Fellowship at Jeddah. 2. Assistant professor of family medicine, Consultant Family Medicine, Family Medicine Department, King. 3. Consultant of orthodontics, SBO program director at KAU. 5. General Dentist, Yasser Medical Center, Jeddah, KSA. 7. Dentistry Program, Batterjee Medical College, KSA. 8. General Dentist, Adwaa Smile Medical Company, Jeddah, KSA. 9. General Dentist, Alqimmah Clinic, Khobar, KSA. Obstetrics and Gynecology Physician, King Fahad Armed Forces Hospital, Jeddah, KSA

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