A cross sectional study of neutrophil to lymphocyte ratio in patients with benign paroxysmal positional vertigo

Abstract

Background: Benign paroxysmal position vertigo (BPPV) is a disorder which arises due to problem in inner ear. It is the most common cause of vertigo. Aim: This study evaluates the hs CRP, ESR, NLR, PLR, MHR and bilirubin levels in BPPV patients and compare with levels in healthy subjects. Materials and Methods: This study is a prospective study which was conducted with 120 newly diagnosed BPPV patients and in 90 patients, age and sex matched. Results: The patients were aged between 15 and 75 years. Females were higher than males in both the groups. Smoking rate was higher in-patient group when compared to the control group. Significant lower levels were observed in BPPV patients for vitamin B12, haematocrit, creatinine, urea, fT4, lymphocyte, total, direct, indirect bilirubin levels. HDL, SGOT, ESR values were significantly higher in BPPV patients. Mean neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), MPV values were higher significantly in BPPV patients when compared to healthy control patients. Neutrophil, platelet, monocyte, MHR, CRP were almost similar in both the groups. Conclusion: The potential biomarkers of BPPV were neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), MPV, erythrocyte sedimentation rate (ESR) and bilirubin levels. The NLR levels were significantly higher in BPPV patients.