A Cross Sectional Observational Study to Assess Clinical Characteristics, Prescription Pattern and Health Related Quality of Life in Migraine Patients at Tertiary Care Teaching Hospital

Abstract

Published on:August 2022Journal of Young Pharmacists, 2022; 14(3):314-321Original Article | doi:10.5530/jyp.2022.14.62 Authors: Rajesh Hadia1, Vidhi Kapadi1, Kushal Parekh1, Sunetra Naidu1, Sanjay Prakash2, Vikas Chandrakar1, Hemraj Singh Rajput1 1Department of Pharmacy Practice, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, INDIA. 2Department of Neurology, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, INDIA. Abstract: Objectives: The present study was focused on assessing the clinical characteristics which include the symptom profile, triggering factors, prescription pattern, headache-related disability, and its impact on patients’ HRQoL. Methods: A cross-sectional observational study was conducted from October 2019 to March 2020 at the Department of Neurology, Dhiraj General Hospital-Vadodara. The data was collected from the prescription prescribed by the respective neurologist and by filling a pre designed questionnaire. All patients who met the inclusion criteria enrolled in a study. Results: In this study, the incidence of migraine is higher in females (78%), than males (23%). The majority of patients were having a severe disability and severe impact on HRQoL with high MIDAS (Migraine Disability Assessment Scale) and HIT-6 (Headache Impact Test-6) scores in opposing MSQoL v2.1 [Migraine Specific Quality of Life (Version 2.1)] where the majority of patients gained less score showing poor quality of life. A higher MIDAS score was observed in chronic migraineurs than episodic migraineurs (32.42 ±18.65 and 30.15 ±18.93) while HIT-6 showed a comparable score (63.98 ±6 and 63.38 ±6.29). Unlike MIDAS and HIT-6, MSQoL v2.1 showed less scores in chronic migraineurs than episodic migraineurs (45.66 ±22.59 and 48.82 ±23.77) which depicts that chronic migraineurs had a poor health-related quality of life than the episodic migraineurs. Conclusion: To conclude, healthcare professionals routinely evaluate the quality of life and related disability to determine whether patients are receiving effective treatment and whether any additional treatment strategies are warranted to enhance QOL.Keywords: Migraine, Health-related quality of life, MIDAS, HIT-6, MSQoL v2.1.