Abstract
Heterostructures have potential to blend the advantages of each material, even exhibiting the evolutionary performance due to synergistic effects. Herein, covalent organic polymers (NUF) are integrated with a TiO2/Ti3C2Tx nanocomposite (TiO2/TiCT) to form TiO2/TiCT-NUF heterojunctions as an enlarged nonenzymatic biosensor for dopamine (DA) and uric acid (UA). Detection is performed by differential pulse voltammetry (DPV). TheTiO2/TiCT/NUF exhibits high sensing activity with low detection limits of 0.2 and 0.18nM (S/N = 3) inthe concentration ranges from 0.002 to 100μM and 0.001 to 60μM for simultaneous determination of DA and UA, respectively. In addition, the TiO2/TiCT/NUF provides good selectivityand reproducibility for DA and UA detection in urine and serum samples with recoveries of 98.4 to 100.9%. The proposed heterojunctions manifest an intriguing potential as a candidate of an electrochemical sensor for sole and simultaneous detection of DA and UA.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
