Abstract
Problem statement: The temperature variation in heterogeneous three layered biological tissues was investigated. Approach: The blood perfusion was considered to be temperature dependent. The heating modalities were taking to go on simultaneously in each of the regions on the one hand and also sequentially in another arrangement. The asymptotic series solution was modified for the three layers and the matching were done at the interface of the regions where there is electric field effect and where there is none. Results: The result revealed there was a clear difference from the temperature pattern when the heating modality was done simultaneously compared to when done sequentially. The thickness of the tissues layer has effect on temperature pattern. Conclusion: A lot of attention must be taken to determine tissue thermophysical properties before therapy was applied. The regional body heating was preferred to spare surrounding normal tissue as against the whole body heating procedure.
Highlights
Hyperthermia has been found to be one of effective therapeutic means of destroying cancerous cells
He did a lot of experiments to measure temperature distribution as a function of radial position in the forearm of nine human subjects. His data showed a temperature differential to three or four degrees between the Skin and the interior arm, which he attributed to the effects of metabolic heat generation and transfer through perfused blood. He proposed a model describing the effects of both metabolism and blood perfusion on the energy balance within the tissue
Many other studies undertaken by Adebile and Akintewe (2006) and Adebile et al (2008), has revealed the need for a great care in hyperthemic therapy in an attempt to protect surrounding living tissues for different BioThermophysical properties of biological tissues
Summary
Hyperthermia has been found to be one of effective therapeutic means of destroying cancerous cells. Adebile et al (2006) did an investigation into the uniqueness and existence of self similar solution for the coupled Maxwell’s and Penne’s Bio heat equations. Hwang and Lemonier (1995) studied on coupling numerical solutions of bio heat transfer and Maxwell’s equations during hyperthermia. They predicted thermal processes within the tissue using steady state bio heat equations which they solved by the finite element method using C-continuity and three nodded isoparametirc elements.
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