Abstract
Background: The purpose of this survey is to estimate profitability of using baclofen solution administered by an implanted programmable pump in treatment of spastic cerebral palsy in comparison to standard therapy of spasticity in Poland. Methods: The cost-utility analysis of intrathecal baclofen treatment was performed from the perspective of public payer in 6 years' time horizon, using Markov model, constructed in the frame of computer program TreeAge® Pro Suite 2008. The target population are children with severe spasticity in cerebral palsy which is refractory to current treatment options. Annual discount rate was set equal to 5% both for costs and the health effects. Assumptions of the analysis were tested in one- and multiway sensitivity analysis. Results: A gain of one quality adjusted life year (QALY) in child with spasticity costs 60 224 PLN (17 126 €) when standard treatment is replaced with baclofen pump therapy. Conclusion. Intrathecal baclofen pump therapy in children with spastic cerebral palsy is a cost-effective strategy in Poland.
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