Abstract
Infertility is a global problem. It has been viewed as a discredit and social humiliation thrust upon healthy young adults. The present detects the glycogen content in the endometrial glands of infertile women in the age group of 18 -39 years. This study aimed to compare infertility and the glycogen content in the endometrial glands of fertile women of the same age group. The endometrium is the tissue of attention because it is the site for implantation of ovum. The current study was done to evaluate the glycogen content in the endometrium of infertile patients and compare it with that of fertile patients. This study was done on 60 cases and 20 controls. Our study showed that large masses of glycogen (++++) was seen in only 7 secretory endometria in infertile cases (14.9%) when compared to 14 secretory endometria infertile subjects (77.7%). Also, endometrial glycogen grading in the secretory phase in infertile patients showed glycogen depletion (Grade 0) in 13 cases (27.7%) whereas it was nil in the fertile group. Glycogen is an essential and straight source of nutrient for the primary concepts and also helps in the successful implantation of blastocyst and continuation of pregnancy.
Highlights
Infertility is a global problem and observed as a discredit and public stigma drive upon healthy young adults
Cases- 60 endometrial biopsies obtained from premenstrual Dilatation and curettage (D&C) done on women in the age group of 20 – 40 years with primary and secondary infertility, received from the Department of Obstetrics and Gynaecology (OBG), Sree Balaji Medical College and Hospital (SBMCH), for histopathological examination were included in the study
Control- 20 endometrial biopsies obtained from premenstrual D&C done on women in the age group of 20 -40 years with proved fertilitywere included ascontrols
Summary
Infertility is a global problem and observed as a discredit and public stigma drive upon healthy young adults. According to American Fertility Society, marriage is to be considered infertile when pregnancy has not happened after one year of sexual intercourse without contraception [2]. The survival and development of embryo is completely dependent on the secretions present in the epithelial cells lining the uterus [5]. These secretions termed as his tiotroph, are rich in glycogen and has been hypothesized in playing a vital role in the development of blastocyst as early as third century B.C. by Aristotle [6]. Endometrial glycogen is one of the most vital factors for the nutrition and progress of blastocyst in the initial periods of gestation. The present study is done to detectthe glycogen content in the endometrium of infertile women and to compare it with the glycogen content in endometrium of fertile women
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