Abstract
AbstractIndolo[2,3‐b]carbazole‐6,12‐dione is exceptionally attractive due to its efficient antitumor activity. Synthesis of biologically potent symmetric indolo[2,3‐b]carbazole‐6,12‐dione and its N‐alkylated derivatives has been achieved by exploring the keto group of easily accessible 2,3,4,9‐tetrahydro‐1H‐carbazol‐1‐one with remarkable yields just in five steps, utilizing the two classical reactions—Japp‐Klingemann procedure followed by Fischer Indole Cyclisation as key steps. The required formylation of N‐alkylated 2,3,4,9‐tetrahydro‐1H‐carbazol‐1‐one has been effectively accomplished through Cross Claisen Condensation.
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