Abstract

Herein, we report a novel approach for the synthesis of π-conjugated peptide-based donor–acceptor (D-π-A) chromophores, by reacting electron-rich alkynes with tetracyanoethylene. The desired tetracyanobutadiene-scaffolded peptides were obtained in good yields with various optical properties, λ max: 321–492 nm, ε: 21,000–65,000 mol −1 dm 3 cm −1 depending on the substitution pattern of the cyanobutadiene scaffold.

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