Abstract

A convenient procedure for the preparation of 3-functionalized 5-alkoxymethyl- and 5-phenoxymethyl-2(5H)-furanones is described. The method is based on the condensation of various β-alkoxy- or β-phenoxy-α-hydroxy ketones with β-activated esters in the presence of catalytic amounts of sodium methoxide. Results are reported showing the possible transformations of these 2(5H)-furanones into related epoxy and α-methylene lactones.

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