Abstract

Ring-fluorinated β-hydroxy α-amino methyl esters 3b, c were synthesized enantioselectively using Sharpless asymmetric aminohydroxylation. These were converted to 2-fluoro- and 6-fluoro-(2 S,3 R)- threo-(3,4-dihydroxyphenyl)serine 1b, c using our previously published procedure.

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