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Abstract
1. The effects of hypercapnia (PwCO2=5 Torr; pH=6.66) at 15°C on acid-base status (PaCO2, pHa, [HCO3−] and (CO3−−]), ventilation (PaCo2) and Cl− concentration were investigated in trout. They were compared with the effects of a change in pHw (7.90→6.666) without a change inPWCO2 (0.25 Torr) and with the effects of a change inPWCO2 (0.25 Torr→5 Torr) without a change in pHw (6.66). 2. The use of an extracorporeal blood circulation has made it possible to obtain information on the time course of modifications in acid-base status of blood during hypercapnia. 3. A technique of data processing was developed which would allow correction of signal distorsion due to the response time of the electrodes. 4. The results show that hypercapnia induces mixed respiratory and metabolic acidosis which is partially compensated within 30h by adjustment of plasma [HCO3−] and [CO3−−] levels.
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