Abstract
AbstractThe hypoglycemic activity of insulin delivered via the various routes is commonly determined by measuring glucose levels in the whole blood samples taken intermittently at frequent intervals. This procedure is usually performed in the anaesthetized animals, however, the glucose levels determined could be higher than those in the conscious animals. Furthermore, the animals are usually excited by direct contact with the investigator during the frequent blood sampling in conscious state, which could cause the glucose level to be higher than at undisturbed state. To overcome these problems, a continuous blood glucose monitoring system was developed by connecting the sensor chamber of a glucose analyzer (YSI Industrial Analyzer model 27), which utilizes glucose oxidase for glucose measurement, to a peristaltic pump with a specially designed mixing chamber and a data acquisition station. By using this system, the hyper-/hypoglycemic activity of glucagon/insulin formulations in the conscious animals, aft...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
