Abstract
AbstractA divergent and enantioselective procedure for synthesis of 2,3‐disubstituted indolines was developed through Brønsted acid/palladium‐complex promoted condensation/reductive alkylation/ hydrogenation cascade reactions from simple amino ketones and aldehydes in one operation. Five Brønsted acid‐promoted steps and two Pd‐catalyzed hydrogenation steps were involved in this process. This strategy provides facile synthesis of structurally diverse multi‐substituted chiral indolines.
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