Abstract
A short and efficient stereoselective synthesis of dihydroxy styryllactone 7- epi-goniodiol has been achieved in nine steps and 20% overall yield, starting from readily available L-erythrose monoacetonide. The key steps of the synthesis involved a stereocontrolled Grignard reaction, a Stille–Gennari reaction and a one-pot acetonide deprotection-lactonisation.
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