Abstract

A new two-step approach for the synthesis of 6H-indolo[2,3-b]quinolines is described using indole C3 alkylation and a one-pot reduction–cyclization–aromatization sequence. The synthesis of the parent 6H-indolo[2,3-b]quinoline system constitutes a formal synthesis of the alkaloid neocryptolepine (cryptotackieine).

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