Abstract

A computer method for calculation of the pharmacokinetic parameters of drugs after multiple dosing is described. It is shown that the program can be used to calculate the pharmacokinetic parameters of sulphadimethoxine in pigs and rabbits. The program can be used in calculations of kinetic parameters even in cases where few blood samples are taken. This method for the calculation of pharmacokinetic parameters after repetitive dosing as a new approach in an endeavour to obtain more useful pharmacokinetic parameters is discussed.

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