A COMPREHENSIVE SURVEY OF COVID–19 DETECTION USING CLOSED MOLECULAR TECHNIQUES IN THE URBAN CITY OF GUJARAT

Abstract

At the end of 2019 a novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing severe acute respiratory syndrome amplied globally from Wuhan, China. In March 2020 the World Health Organization (WHO) declared the SARS-Cov-2 virus a global pandemic. The disease is spread through inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 days. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, weakness others. The disease is moderate in most people. It may continue to pneumonia, acute respiratory distress syndrome (ARDS), and multi-organ dysfunction. Many people are asymptomatic. Diagnosis is by the presentation of the virus in respiratory secretions by special molecular tests. Common laboratory ndings include normal and or low white cell counts with elevated C-reactive protein (CRP). The computerized tomographic chest scan is usually abnormal even in those with asymptomatic or mild disease. Prevention leads to home isolation of suspected cases and those with mild illnesses and strict infection control measures at hospitals that include contact and droplet precautions. Due to the current review, we summarized and equally analyze the emergence and pathogenicity of COVID 19 infection and previous human coronavirus severe acute respiratory coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERSCoV). In Particular, focus on public health impact, pathophysiology and clinical manifestation, diagnosis, case management.