Abstract
Plant-based systems continue to play an essential role in healthcare, and their use by different cultures has been extensively documented. Asphodelus L. (Asphodelaceae) is a genus of 18 species and of a total of 27 species, sub-species and varieties, distributed along the Mediterranean basin, and has been traditionally used for treating several diseases particularly associated with inflammatory and infectious skin disorders. The present study aimed to provide a general review of the available literature on ethnomedical, phytochemical, and biological data related to the genus Asphodelus as a potential source of new compounds with biological activity. Considering phytochemical studies, 1,8-dihydroxyanthracene derivatives, flavonoids, phenolic acids and triterpenoids were the main classes of compounds identified in roots, leaf and seeds which were correlated with their biological activities as anti-microbial, anti-fungal, anti-parasitic, cytotoxic, anti-inflammatory or antioxidant agents.
Highlights
The genus Asphodelus Linnaeus belongs to family Asphodelaceae Jussieu and is native to temperateEurope, the Mediterranean, Africa, the Middle East, and the Indian Subcontinent, and naturalized in other places (New Zealand, Australia, Mexico, southwestern United States, etc.) [1]
Ethnomedicinal records showed that among the 18 species of the genus Asphodelus, only five species namely A. aestivus, A. fistulosus, A. microcarpus, A. ramosus, and A. tenuifolius have been documented for their traditional uses (Table 1)
A. aestivus, A. fistulosus and A. microcarpus were reported to be used in dermatomucosal infections in various countries including Cyprus, Egypt, Libya, Palestine, and
Summary
The Mediterranean, Africa, the Middle East, and the Indian Subcontinent, and naturalized in other places (New Zealand, Australia, Mexico, southwestern United States, etc.) [1]. It reaches its maximum diversity in the West of the Mediterranean, in the Iberian Peninsula and in. This botanical family, called Asphodelaceae, has had a complex history; its circumscription and placement in an order have varied widely. In the Cronquist system of 1981, members of the Asphodelaceae were placed in the order Liliales Perleb [3,4]. Cronquist had difficulty classifying the less obviously delineated lilioid monocots; he placed taxa from both the modern orders
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