Abstract
<p class="nova-e-paragraph"><em>Polygonum glabrum </em>commonly<em> </em><em>called as </em>dense flower knotweed <em>is a</em> perennial plant. It is an amphibious shrub<em> with </em>pink flowers and glossy brown seeds <em>found in most parts of India. Various parts of the plant </em>like leaves, stem, flowers and roots are used in traditional system of medicine. Traditionally, different decoctions/infusions are prepared using the <em>plant</em> parts and given for the treatment of rheumatism, jaundice, piles etc. From pharmacological point, the plant has been effectively screened for antihepatotoxic, antinephrotoxic, antimicrobial, anticancer, antidepressant, analgesic and antioxidant activities. The plant contains many flavonoids including diosmetin, rutin, hyperin and quercitrin. The lanceolate leaves are rich in essential oil which contains many compounds like 6, 6-dimethyl-1, 3-heptadien-5-ol, oleicacid, 9-octadecenamide, isodecyloctyl ester and 1,2,3-benzenetriol. Compounds like aliphatic, alicyclic compounds, sesqueterpenes, sterols, phenolic acids as well as other trace elements have been identified in the plant. This review provides morphological, ethnomedical, pharmacological and phytochemical data of the plant <em>Polygonum glabrum.</em></p>
Highlights
Polygonum glabrum which is commonly called as dense flower knotweed is a semi aquatic perennial plant
It belongs to the family polygonaceae and genus polygonum [1]
In south India Polygonum glabrum leaves are used for the treatment of dysentery [13]
Summary
Polygonum glabrum which is commonly called as dense flower knotweed is a semi aquatic perennial plant. In south India Polygonum glabrum leaves are used for the treatment of dysentery [13]. Owing to its traditional use Polygonum glabrum has been studied for different types of pharmacological activities. The aqueous extract of leaves of Polygonum glabrum was studied for their anti depressant activity in different models like behavioural despair test, tail suspension test and L-dopa induced hyperactivity & aggressive behavior test.
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