Abstract
Filifoliumsibiricum (L.)Kitam (F.sibiricum), a compositae plant, is especially used to inhibit drug-resistant bacteria in folk medicine. Modern pharmacological studies also confirmed a variety of pharmacological properties about sedative activities, antibacterial activity, anti-inflammatory activity, analgesic activities, antitussive and asthma relieving. In this paper, the research progress of F.sibiricum in botany, ethnopharmacology, phytochemistry, pharmacology, pharmacokinetics and toxicology was reviewed. Prospects for future investigation and application of this herb were also discussed. Information on F.sibiricum was gathered from various sources, including books on traditional Chinese herbal medicine and scientific databases such as PubMed, Google Scholar, Science Direct, Baidu Scholar, CNKI and other professional websites. The results indicate that ~ 66 chemical compounds were isolated and identified from F.sibiricum. Among them, flavonoids are generally considered to be the main bioactive and characteristic ingredients. F.sibiricum is a traditional Chinese medicine with pharmacological activities such as the immune system, nervous system, respiratory system and cardiovascular and cerebrovascular systems. Most importantly, we should concentrate on developing new drugs related to F.sibiricum, so as to exert greater potential for treatment.
Highlights
Filifolium sibiricum (L.)Kitam is known as “Xian Yeju” or “Tu Maohao” in Chinese. It is a necessary herb with other aliases, namely Tanacetum sibiricum L (Latin) included in the national compilation of Chinese herbal medicine and Siberian Filifolium herb recorded in the dictionary of traditional Chinese medicine [1]
Flavones Recent studies have confirmed that F. sibiricum is rich in flavonoids, which is considered as the active components of this plant medicine
The results showed that all the mice in the bacterial infection group died within 24 h after infection with penicillin-resistant Staphylococcus aureus
Summary
Filifolium sibiricum (L.)Kitam is known as “Xian Yeju” or “Tu Maohao” in Chinese. It is a necessary herb with other aliases, namely Tanacetum sibiricum L (Latin) included in the national compilation of Chinese herbal medicine and Siberian Filifolium herb recorded in the dictionary of traditional Chinese medicine [1]. Studies certify that developing some new anti-infective active substances from natural herbs for the new drugs to treat drug-resistant bacterial infections is a direct and effective method. It provides the possibility for improving the situation of antibiotic abuse and drug-resistant superbugs. As documented in the Compendium of Materia Medica, the achievements of herbology in China over the past two thousand years were systematically summarized and reflected the scientific achievements of contemporary Chinese medicine [13] This herb has the effect of clearing away heat and toxic materials, regulating menstruation and calming nerves, and is mainly. Flavones Recent studies have confirmed that F. sibiricum is rich in flavonoids, which is considered as the active components of this plant medicine.
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