Abstract

It is assumed that approximately 24–66% of patients with liver cirrhosis develop malnutrition. Numerous pathological processes lead to serious disorders of nutritional status in this group of patients. Malnutrition in the course of liver cirrhosis is associated with increased morbidity, complications, and low quality of life. Under these conditions, detection of malnutrition is of crucial importance. This review explores the complex mechanisms that lead to malnutrition in the course of liver cirrhosis and focuses on methods used in the assessment of nutritional status in cirrhotic patients. Among others, the role of bioelectrical impedance is highlighted. This noninvasive tool is promising and quite an accurate method of estimating body composition.

Highlights

  • It is assumed that approximately 24–66% of patients with liver cirrhosis develop malnutrition

  • This review explores the complex mechanisms that lead to malnutrition in the course of liver cirrhosis and focuses on methods used in the assessment of nutritional status in cirrhotic patients

  • The muscular uptake of branched-chain amino acids (BCAAs) increases [28]. Another pathological aspect of BCAAs is their influence on muscle metabolism, which is reflected by glutamine synthesis from ammonia fixation together with inhibition of proteolysis

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Summary

Introduction

It is assumed that approximately 24–66% of patients with liver cirrhosis develop malnutrition. This review explores the complex mechanisms that lead to malnutrition in the course of liver cirrhosis and focuses on methods used in the assessment of nutritional status in cirrhotic patients. 1. Malnutrition in the Course of Liver Cirrhosis and Methods of Nutritional Status Assessment—General Data

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